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Related post: 16-8 PHS 6040 (Rev. 1/83) GPO 895-100 DEPARTMENT OF HEALTH AND HUMAN SERVICES- PUBLIC HEALTH SERVICE NOTICE OF INTRAMURAL RESEARCH PROJECT PROJECT NUMBER ZOl AI 00383-01 OSD PERIOD COVERED October 1, 1982 to September 30, 1983 TITLE OF PROJECT (80 characters or leu. Title mu$t fit on one line between the borders.) Acquisition of Specimens from Cases of Acquired Immune Deficiency Syndrome PRINCIPAL INVESTIGATOR (LUt other profeaelonal personnel on subsequent pages.) (Name, title, laboratory, and institute affiliation) Richard G. Wyatt, M.D., Medical Officer, OSD/NIAID COOPERATING UNITS (if any) Dr. Louis Baker, New York Blood Center and Memorial Sloan Kettering Cancer Center and Dr. Jonathan Gold, New York Blood Center and Memorial Sloan Kettering Cancer Center LAB/BRANCH Office of the Scientific Director INSTITUTE AND LOCATION National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20205 TOTAL MANYEARS: 0.2 PROFESSIONAL: 0.1 OTHER: 0.1 CHECK APPROPRIATE BOX(ES) 5p (a) Human subjects □ (a1) Minors 6tll {a2) Interviews (13 (b) Human tissues □ (c) Neither SUMMARY OF WORK (Use standard unreduced type. Do not exceed the space provided.) The Purchase Antabuse Online etiology of Acquired Immune Deficiency Syndrome (AIDS) is not known, although currently a variety of microbial agents has been proposed as playing causative role. Since opportunistic infections Generic Antabuse with Antabuse Online a variety of such viral, bacterial, fungal and parasitic agents occurs characteristically in AIDS, the question of whether an agent is etiologic or opportunistic arises frequently. The recovery Purchase Antabuse of an infectious agent(s) or the demonstration of an antibody re- sponse to such an agent prior to the diagnosis of AIDS would provide evidence for primary infection with a putative Order Antabuse etiological agent. The major obstacle to efforts directed at cultivation or serological char- acterization of putative etiological agents has been the availability of early specimens obtained prior to the onset of AIDS. These specimens would Cheap Antabuse be most likely to contain the agent, and even earlier sera would be required to represent pre-exposure sera. In response to these needs, an intramural research contract was developed with the New York Blood Center and Memorial Sloan Kettering Cancer Center to collect specimens in a prospective fashion from 325 homosexual males. Three populations are being recruited: patients with lymphadenopathy (100), normal plasma donors (175) and normal homosexual males from a geographically distinct area in New York State (50). Specimens of peripheral blood leukocytes, plasma, serum, semen, urine, saliva and stool will be collected at 1 to 4 month intervals along with epidemiological information. Specimens will be stored in an NIAID Repository until cases of AIDS are identified in the study population. At that time, appropriate specimens will be studied intensively for the presence of agents, and paired sera will be examined for the development of antibody Buy Cheap Antabuse to i^arious candidate agents. 16-9 _^ PHS 6040 (Rev. 1/83) GPO 895-100 DEPARTMENT OF HEALTH AND HUMAN SERVICES - PUBLIC HEALTH SERVICE NOTICE OF INTRAMURAL RESEARCH PROJECT PROJECT NUMBER ZOl AI 00384-01 OSD PERIOD COVERED October 1, 1982 to September 30, 1983 TITLE OF PROJECT (80 charaetert or Uu. Title muit fit on one line between the borden.) Evaluation of Immunologic Abnormalities in AIDS Patients PRINCIPAL INVESTIGATOR (LUt other profeulonal perionnel on tubtequent page:) (Name, title, laboratory, and ln$tttute affiliation) Thomas Folks, Ph.D., Staff Fellow, Buy Antabuse Online LIG, NIAID COOPERATING UNITS wony; p^ _ Anthony Fauci, LIR/NIAID; Dr. Clifford Lane, LIR/NIAID; Dr. Steven Straus, LCI/NIAID; Dr. Louis Baker, NYBC; Dr. Jonathan Gold, Memorial Sloan Buy Antabuse Kettering; Dr. Donald Armstrong, Memorial Sloan Kettering; Dr. Robert RpHfjpiH^ Walter Reed Army Hospital lab/branchT Office of the Scientific Director NSTITUTE AND LOCATION National Institute of Allergy and Infectious Diseases, NIH, Order Antabuse Online Bethesda, MP 20205 TOTAL MANYEARS: 3.1 PROFESSIONAL: 1.5 1.6 CHECK APPROPRIATE BOX(ES) □ (a) Human subjects □ (a1) Minors □ (a2) Interviews [xi (b) Hunian tissues □ (c) Neither SUMMARY OF WORK (U$e itandard unreduced type. Do not exceed the tp ace provided.)
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